Mistry 2016.

Study characteristics
Methods	Study design: RCT, split‐mouth Conducted in: India
Participants	Inclusion criteria: only those patients having same angulation, same depth from the occlusal surface of the adjacent second molar, and the same ramus relation, i.e. same difficulty index bilaterally as described by Pederson, in whom bony osteotomy was necessary were selected for the study Exclusion criteria: patients having pericoronitis, acute alveolar abscess, oral submucous fibrosis, on antibiotics for any infection, who consumed alcohol or who smoked tobacco and were not willing to give consent for the study were excluded. 30 cases in total were selected for the study. Age: > 18 Number randomised: 30 participants/60 teeth
Interventions	Piezosurgery versus conventional Group 1 (n = 30): conventional Group 2 (n = 30): piezosurgery
Outcomes	Pain VAS (0 to 10) Trismus: measured as the distance between the mesial incisal corner of the right upper and lower central incisors with the help of metallic scale. Measurements were recorded in millimetre unit and were noted preoperatively, postoperatively immediately after the surgical procedure, and then on postoperative days 1, 3, 5, 7, and 15 in both groups. Swelling: distances between extra oral and intra oral by the use divider
Notes	Sample size calculation: not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Comment: authors state the grouping was done randomly, however the method of randomisation is not described
Allocation concealment (selection bias)	Unclear risk	Comment: concealment methods are not described
Blinding (performance bias and detection bias) patient	Unclear risk	Comment: consent was given by the participant, but it is unclear whether they were informed of the equipment details, etc.
Blinding (performance bias and detection bias) assessor	Unclear risk	Comment: blinding of the assessor is not mentioned
Incomplete outcome data (attrition bias) All outcomes	Low risk	Comment: no dropouts were reported
Selective reporting (reporting bias)	Low risk	Comment: all planned outcomes were reported
Other bias	High risk	Comment: carry‐over effect was not analysed. The grouping of participants was reported to be randomised (piezo vs conventional technique), however the side that was chosen for the test/control was not described as randomised.