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. 2020 Jul 26;2020(7):CD004345. doi: 10.1002/14651858.CD004345.pub3

NCT02495207.

Study name A comparison between conventional surgery and piezosurgery
Methods Parallel RCT
Participants 15 participants
Interventions Piezosurgery
Outcomes Primary outcome measures: levels of heat shock protein 70 (time frame: 5 minutes before third molar removal with the last removed layer of bone). This will be measured using ELISA (enzyme‐linked immunosorbent assay) methodology.
Secondary outcome measures: percentage of viable bone cells (time frame: this variable will be measured from the specimens taken within the first 15 minutes of bone cutting to remove third molars). Percentage of viable bone cells will be calculated based on the counts of viable bone cells observed under the microscope.
Starting date 19 June 2015
Contact information Department of Oral and Maxillofacial Surgery, University of Damascus Dental School/ Damascus, Damascus, Syrian Arab Republic
Notes Official title: A histo‐immunological comparative study of bone cutting by conventional surgery and piezosurgery on the secretion of heat shock protein 70 (HSP70) and on the bone cells
clinicaltrials.gov/ct2/show/NCT02495207