2. Template for 'Summary of findings' table.

General anaesthesia compared with local anaesthesia for acute ischaemic stroke endovascular treatment
Patient or population: adults with acute ischaemic stroke endovascular treatment Settings: community Intervention: general anaesthesia Comparison: local anaesthesia
Outcomes	Illustrative comparative risks* (95% CI)		Relative effect (95% CI)	No of participants (studies)	Certainty of the evidence (GRADE)	Comments
	Risk with local anaesthesia	Risk with general anaesthesia
	[control]	[experimental]
Functional outcome at the end of the scheduled follow‐up	[value] per 1000	[value] per 1000 ([value] to [value])	RR [value]([value] to [value])	[value] ([value])	⊕⊝⊝⊝ very low ⊕⊕⊝⊝ low ⊕⊕⊕⊝ moderate ⊕⊕⊕⊕ high
Neurological impairment	[mean difference](CI)	[mean difference](CI)	‐	[value] ([value])	⊕⊝⊝⊝ very low ⊕⊕⊝⊝ low ⊕⊕⊕⊝ moderate ⊕⊕⊕⊕ high
Stroke‐related mortality	[value] per 1000	[value] per 1000 ([value] to [value])	RR [value]([value] to [value])	[value] ([value])	⊕⊝⊝⊝ very low ⊕⊕⊝⊝ low ⊕⊕⊕⊝ moderate ⊕⊕⊕⊕ high
All intracranial haemorrhage	[value] per 1000	[value] per 1000 ([value] to [value])	RR [value]([value] to [value])	[value] ([value])	⊕⊝⊝⊝ very low ⊕⊕⊝⊝ low ⊕⊕⊕⊝ moderate ⊕⊕⊕⊕ high
Target artery revascularisation status	[value] per 1000	[value] per 1000 ([value] to [value])	RR [value]([value] to [value])	[value] ([value])	⊕⊝⊝⊝ very low ⊕⊕⊝⊝ low ⊕⊕⊕⊝ moderate ⊕⊕⊕⊕ high
Time to revascularisation	[value] per 1000	[value] per 1000 ([value] to [value])	RR [value]([value] to [value])	[value] ([value])	⊕⊝⊝⊝ very low ⊕⊕⊝⊝ low ⊕⊕⊕⊝ moderate ⊕⊕⊕⊕ high
Adverse events	[value] per 1000	[value] per 1000 ([value] to [value])	RR [value]([value] to [value])	[value] ([value])	⊕⊝⊝⊝ very low ⊕⊕⊝⊝ low ⊕⊕⊕⊝ moderate ⊕⊕⊕⊕ high
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: confidence interval; RR: risk ratio
GRADE Working Group grades of evidence High certainty: we are very confident that the true effect lies close to that of the estimate of the effect. Moderate certainty: we are moderately confident in the effect estimate; the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low certainty: our confidence in the effect estimate is limited; the true effect may be substantially different from the estimate of the effect. Very low certainty: we have very little confidence in the effect estimate; the true effect is likely to be substantially different from the estimate of effect.