Summary of findings 3. General anesthesia with premedication.
| Study | Fentanyl$ | Alfentanil$ | Midazolam (benzodiazepine)* | Propofol* | Thiopental (barbiturate)* | Desflurane# | Enflurane# | N2O2# | Opioid | Non‐selective COX | Selective COX |
| Bone | x | c | c | c | Nalbuphine vs fentanyl | ||||||
| Dahl | c | c | c | c |
Paracetamol with codeine | Paracetamol (COX 3) vs placebo | |||||
| Heath | c | c | c | dihydrocodeine vs placebo | |||||||
| Hein 1999 | c | c | c | Paracetamol vs placebo | |||||||
| Hein 2001 | c | c | c | Lornoxicam | Paracetamol | ||||||
| Jakobsson 1996 | c | c | c | Sodium‐diclofenac vs ketorolac vs potassium‐diclofenac vs NaCl | |||||||
| Liu | c | c | c | Etoricoxib vs placebo (COX 2) |
Opiates$, Sedative hypnotic agents*, Inhalational anesthetic#
x= control or intervention, c= co‐treatment