Table 3.
The sensitivity of probiotic candidates against 30 antibiotics
| Types of Drugs | Drug | μg/pill | HSM-1 | HSM-10 | HSM-14 | HSM-18 |
|---|---|---|---|---|---|---|
| Penicillins | Penicillin | 10 U | 39 (S) | 39(S) | 37(S) | 38(S) |
| Oxacillin | 1 | 27 (S) | 19(I) | 20(I) | 22(S) | |
| Carboxycillin | 100 | 42 (S) | 44(S) | 33(S) | 40(S) | |
| Piperacillin | 100 | 48 (S) | 29(S) | 37(S) | 42(S) | |
| Ampicillin | 100 | 31 (S) | 35(S) | 31(S) | 32(S) | |
| Cephalosporins | Cephalexin | 30 | 33 (S) | 40(S) | 29(S) | 28(S) |
| Cefazolin | 30 | 47 (S) | 25(S) | 27(S) | 45(S) | |
| Cefradine | 30 | 34 (S) | 44(S) | 27(S) | 32(S) | |
| Ceftazidime | 30 | 28 (S) | 44(S) | 17(I) | 29(S) | |
| Cefoperazone | 75 | 41 (S) | 40(S) | 29(S) | 37(S) | |
| Cefatriaxone | 30 | 41 (S) | 38(S) | 26(S) | 35(S) | |
| Cefuroxime | 30 | 48 (S) | 44(S) | 36(S) | 49(S) | |
| Aminoglycosides | Amikacin | 30 | 19 (I) | 19(I) | 11(R) | 24(S) |
| Kanamycin | 30 | 25 (S) | 21(S) | 7(R) | 20(I) | |
| Neomycin | 30 | 22 (S) | 17(I) | 15(R) | 20(I) | |
| Gentamicin | 10 | 22 (S) | 14(R) | 12(R) | 21(S) | |
| Tetracycline | Tetracycline | 30 | 14 (R) | 13(R) | 29(S) | 14(R) |
| Doxycycline | 30 | 22 (S) | 22(S) | 28(S) | 17(I) | |
| Minocycline | 30 | 30 (S) | 27(S) | 35(S) | 26(S) | |
| Macrolides | Erythromycin | 15 | 34 (S) | 29(S) | 28(S) | 32(S) |
| Midecamycin | 30 | 34 (S) | 29(S) | 23(S) | 26(S) | |
| Glycopeptides | Vancomycin | 30 | 31 (S) | 25(S) | 7(R) | 26(S) |
| Quinolones | Norfloxacin | 10 | 18 (I) | 16(I) | 29(S) | 25(S) |
| Ofloxacin | 5 | 32 (S) | 27(S) | 29(S) | 29(S) | |
| Ciprofloxacin | 5 | 27 (S) | 26(S) | 22(S) | 21(S) | |
| Furazolidone | 300 | 23 (S) | 17(I) | 19(I) | 29(S) | |
| Chloramphenicol | 30 | 39 (S) | 36(S) | 36(S) | 36(S) | |
| Clindamycin | 2 | 41 (S) | 37(S) | 27(S) | 40(S) | |
| Sulfonamides | Sulfamethoxazole (SMZ/TMP)△ | 23.75/1.25 | 17 (I) | 18(I) | 8(R) | 20(I) |
| Other classes | Polymyxin | 300 IU | 22 (S) | 5(R) | 7(R) | 24(S) |
Note: The zone of inhibition (diameter in mm) for each antibiotic was measured and expressed as susceptible, S (≥21 mm); intermediate, I (16–20 mm), and resistance, R(<=15 mm)