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. 2009 Jul 8;2009(3):CD006455. doi: 10.1002/14651858.CD006455.pub2

DIMOND.

Methods 12‐week, randomised, double‐blind, parallel study.
Participants 90 HD patients (clinical features of HD and a confirmatory family history of HD, and/or genetically confirmed HD), able to take medication (capsules) by mouth.
Exclusion criteria: unstable medical illness, pregnant or lactating women of those intending to become pregnant during the study period.
Interventions Dimebon 60 mg/day vs placebo.
Outcomes Primary: safety and tolerability.
Secondary endpoint: efficacy on cognitive, motor, and overall function in subjects with Huntington's Disease. Assess the pharmacokinetics of Dimebon.
Notes