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. 2020 Jul 28;19:152. doi: 10.1186/s12934-020-01412-2

Table 1.

Clinical characteristics of the study population divided by puberty status and gender

Pre-puberty (n = 42) Puberty (n = 47)
Male Female P value Male Female P value
N 28 14 21 26
Age (years) 8.53 ± 1.82 8.02 ± 1.22 0.346 11.38 ± 1.31 10.67 ± 0.89 0.033
Height (cm) 134.31 ± 11.63 130.19 ± 7.92 0.241 152.87 ± 7.46 145.80 ± 7.14 0.002
Weight (kg) 41.54 ± 17.75 36.09 ± 9.23 0.198 64.47 ± 9.04 45.72 ± 10.49 < 0.001
BMI (kg/cm2) 22.04 ± 6.31 21.03 ± 3.78 0.524 27.46 ± 2.03 21.33 ± 3.86 < 0.001
BMI-Z 1.71 ± 1.91 2.34 ± 1.49 0.249 2.57 ± 0.39 1.56 ± 1.32 0.001
Estradiol (pg/ml) < 5 < 5 1.000 11.07 ± 8.49 33.68 ± 35.80 0.099
Testosterone (ng/dl) 5.10 ± 4.16 9.40 ± 9.76 0.445 83.20 ± 98.55 13.99 ± 20.87 0.018