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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: ACS Chem Neurosci. 2020 Jun 19;11(13):1937–1943. doi: 10.1021/acschemneuro.0c00093

Figure 4.

Figure 4.

Regulator effect networks affected by largazole, identified through the analysis of RNA-seq data of mice brains (50 mg/kg ip, 12 h treatment) using IPA (2.5-fold cutoff, p < 0.05), showing the anticancer and neuroprotective potential of largazole. CP: canonical pathways. PAX6 and OPRM1 are emphasized in bold face.