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Neurological diseases predicted to be decreased in response to treatment (based on IPA; 2.5-fold cutoff, p < 0.05).
| Diseases or functions annotation | p-Value | Activation z-score | No. of molecules | Selected genes |
|---|---|---|---|---|
| Movement disorders | 1.93E-011 | −3.773 | 149 | OPRM1, PAX6, ATXN2 |
| Seizure disorders | 6.38E-05 | −3.588 | 63 | SYN2, OPRM1, ATXN2 |
| Paraparesis | 0.000152 | −2.236 | 5 | CTSF, NDRG1, PLP1 |
| Ataxia | 0.00015 | −2.775 | 35 | PAX6, SOD2, PLP1 |
| Congenital malformation of brain | 0.00013 | −3.43 | 36 | PAX6, CREBBP, AKT3 |
