Skip to main content
. 2020 May 29;2020(5):CD012947. doi: 10.1002/14651858.CD012947.pub2

Alonso 2010.

Study characteristics
Patient Sampling Cohort study. Methods of patient sampling and recruitment were not reported. Data from both eyes were included in the analysis.
Patient characteristics and setting Sample size: 60 participants, 112 eyes (38 eyes narrow angle and 74 open angle).
Age: mean (SD), 51 ± 12, range 21‐72 years.
Sex: 32 (53.3%) female.
Setting: secondary care.
Country: Brazil.
Ethnicity: not reported.
Exclusions: not reported.
Index tests Scheimpflug photography: HR Pentacam, Oculus Inc, Germany, nasal and temporal angles were studied in the horizontal meridian, cut‐off values were derived from the study data for ACA and ACD.
Target condition and reference standard(s) Static gonioscopy was performed, an occludable angle was classified using a Shaffer grade of 1 (the number of quadrants/degrees occluded were not reported).
Flow and timing There were no uninterpretable test results or exclusions reported. The index test and reference standard were conducted on the same occasion.
Comparative  
Notes Conflict of interest: no conflict of interest statement provided.
Methodological quality
Item Authors' judgement Risk of bias Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled? Unclear    
Was a case‐control design avoided? Yes    
Did the study avoid inappropriate exclusions? Unclear    
Could the selection of patients have introduced bias?   Unclear risk  
Are there concerns that the included patients and setting do not match the review question?     Unclear
DOMAIN 2: Index Test (LACD)
DOMAIN 2: Index Test (Scheimpflug photography)
Were the index test results interpreted without knowledge of the results of the reference standard? Yes    
If a threshold was used, was it pre‐specified? No    
Could the conduct or interpretation of the index test have introduced bias?   High risk  
Are there concerns that the index test, its conduct, or interpretation differ from the review question?     Low concern
DOMAIN 2: Index Test (AS‐OCT)
DOMAIN 2: Index Test (SPAC)
DOMAIN 2: Index Test (Flashlight)
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition? Yes    
Were the reference standard results interpreted without knowledge of the results of the index tests? Yes    
Could the reference standard, its conduct, or its interpretation have introduced bias?   Low risk  
Are there concerns that the target condition as defined by the reference standard does not match the question?     Low concern
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard? Yes    
Were all patients included in the analysis? Yes    
Did all patients receive a reference standard Yes    
Could the patient flow have introduced bias?   Low risk