Choudhari 2019b.
Study characteristics | |||
Patient Sampling | Cross‐sectional study. Phakic participants aged 40 years or older attending a rural eye clinic were examined between June 2001 and January 2003. Data from the right eye were included in the analysis. | ||
Patient characteristics and setting | Sample size: 888 eyes (271 narrow angle and 617 open angle). Age: median 50 IQR (45‐60). Sex: 497 (55.9%) female. Setting: community. Country: India. Ethnicity: Indian. Exclusions: abnormalities that would preclude visualisation of the peripheral ACD, aphakia, pseudophakia, manifest strabismus or insufficient co‐operation. |
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Index tests | LACD: original van Herick grading scheme used (grade 1‐4) performed at the temporal angle. Grade 2 or less was used as the cut‐off (≤ 25%). | ||
Target condition and reference standard(s) | Indentation gonioscopy was performed in dim illumination. An occludable angle was defined as the posterior trabecular meshwork not visible in 2 or more quadrants (≥ 180 degrees). | ||
Flow and timing | There were no participants that were excluded or had uninterpretable results. The index test and reference standard were conducted on the same occasion. | ||
Comparative | |||
Notes | Conflict of interest: no conflict of interest statement provided. | ||
Methodological quality | |||
Item | Authors' judgement | Risk of bias | Applicability concerns |
DOMAIN 1: Patient Selection | |||
Was a consecutive or random sample of patients enrolled? | Yes | ||
Was a case‐control design avoided? | Yes | ||
Did the study avoid inappropriate exclusions? | Yes | ||
Could the selection of patients have introduced bias? | Low risk | ||
Are there concerns that the included patients and setting do not match the review question? | Low concern | ||
DOMAIN 2: Index Test (LACD) | |||
Were the index test results interpreted without knowledge of the results of the reference standard? | No | ||
If a threshold was used, was it pre‐specified? | Yes | ||
Could the conduct or interpretation of the index test have introduced bias? | High risk | ||
Are there concerns that the index test, its conduct, or interpretation differ from the review question? | Low concern | ||
DOMAIN 2: Index Test (Scheimpflug photography) | |||
DOMAIN 2: Index Test (AS‐OCT) | |||
DOMAIN 2: Index Test (SPAC) | |||
DOMAIN 2: Index Test (Flashlight) | |||
DOMAIN 3: Reference Standard | |||
Is the reference standards likely to correctly classify the target condition? | Yes | ||
Were the reference standard results interpreted without knowledge of the results of the index tests? | No | ||
Could the reference standard, its conduct, or its interpretation have introduced bias? | High risk | ||
Are there concerns that the target condition as defined by the reference standard does not match the question? | Low concern | ||
DOMAIN 4: Flow and Timing | |||
Was there an appropriate interval between index test and reference standard? | Yes | ||
Were all patients included in the analysis? | Yes | ||
Did all patients receive a reference standard | Yes | ||
Could the patient flow have introduced bias? | Low risk |