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. 2020 May 29;2020(5):CD012947. doi: 10.1002/14651858.CD012947.pub2

Yu 1995a.

Study characteristics
Patient Sampling Cross‐sectional study, 20% random sample taken from a population over 50 years old from the Doumen county of the Guangdong province in November 1995. Data from both eyes were included in the analysis.
Patient characteristics and setting Sample size: 200 participants, 390 eyes (72 narrow angle and 318 open angle).
Age: not reported.
Sex: not reported.
Setting: community.
Country: China.
Ethnicity: Chinese.
Exclusions: not reported.
Index tests Flashlight: flashlight beam was shown from the temporal side, a cut‐off using 1/4 (grade 2) or <1/4 (grade 1) nasal iris light band ratio were used.
Target condition and reference standard(s) Gonioscopy using Shaffer’s chamber angle grading a grade 2 was considered as occludable in the temporal quadrant (90 degrees).
Flow and timing There were no uninterpretable test results or exclusions reported. The index test and reference standard were conducted on the same occasion.
Comparative  
Notes Conflict of interest: no conflict of interest statement provided.
Methodological quality
Item Authors' judgement Risk of bias Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled? Yes    
Was a case‐control design avoided? Yes    
Did the study avoid inappropriate exclusions? Unclear    
Could the selection of patients have introduced bias?   Unclear risk  
Are there concerns that the included patients and setting do not match the review question?     Low concern
DOMAIN 2: Index Test (LACD)
DOMAIN 2: Index Test (Scheimpflug photography)
DOMAIN 2: Index Test (AS‐OCT)
DOMAIN 2: Index Test (SPAC)
DOMAIN 2: Index Test (Flashlight)
Were the index test results interpreted without knowledge of the results of the reference standard? Unclear    
If a threshold was used, was it pre‐specified? No    
Could the conduct or interpretation of the index test have introduced bias?   High risk  
Are there concerns that the index test, its conduct, or interpretation differ from the review question?     Unclear
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition? Yes    
Were the reference standard results interpreted without knowledge of the results of the index tests? Unclear    
Could the reference standard, its conduct, or its interpretation have introduced bias?   Unclear risk  
Are there concerns that the target condition as defined by the reference standard does not match the question?     Low concern
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard? Yes    
Were all patients included in the analysis? Yes    
Did all patients receive a reference standard Yes    
Could the patient flow have introduced bias?   Low risk