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. 2020 Jul 29;15(7):e0236743. doi: 10.1371/journal.pone.0236743

Fig 4. Incident TB disease rates among household contacts with and without incident TB infection.

Fig 4

A line graph depicting the incident TB disease (iTBD) rates among household contacts (HHC) of adult pulmonary TB (PTB) patients in India, stratified by incident TB infection (iTBI) status which was defined using different TST conversion cut offs (≥ 5 mm, ≥ 10 mm, and ≥ 6 mm increase in induration from previous reading) along with the IGRA conversion cut off of ≥ 0.35 IU/l. The comparison shows that the iTBD estimates were similar for those HHC with and without iTBI, irrespective of the TST or IGRA cutoffs used to define iTBI. In addition, the iTBD estimates were similar irrespective of whether the definition of iTBI was based on the requirement of both a positive TST and IGRA test (“AND”) or either test alone (“OR”).