Table 2. Comparison of our method applied to networks built with different interaction types.

Type	# nodes	# PPI genes	Is TP53 a PPI gene?	Clinvar	Oncokb
Reaction	5583	116	no
Binding	11,049	109	yes	enriched	enriched
Catalysis	5,277	21	no
Activation	5,229	35	yes	enriched
Inhibition	2,802	3	no
Post-translational Modification	2,566	8	no		enriched
Expression	1,460	55	no		enriched
Co-expression	8,231	167	yes