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. 2020 Jul 1;2020(7):CD012011. doi: 10.1002/14651858.CD012011.pub2

Eggert 1988.

Study characteristics
Methods Randomised controlled trial
Participants Inclusion criteria:
  1. Newborns with uncomplicated hyperbilirubinaemia


Exclusion criteria:
  1. Newborns under 40 hours of age with an ABO or Rh incompatibility

  2. Those treated with antibiotics


Mean age in days at recruitment:
Intervention = 3.15
Control = 2.56
Mean body weight in kg of participants:
Intervention = 3.18
Control = 3.16
SDs for these means not reported
Interventions Intervention: Drager 76 phototherapy unit equipped with 6 special blue fluorescent lights (Philips TL 20 W/52BAM blue emission range 410 to 520 nm, maximum 460 nm). Four outer walls of the incubator draped with white cloth additionally
N = 36
Control: Drager 76 phototherapy unit equipped with 6 standard fluorescent lights (Philips TL 20 W/52BAM blue emission range 410 to 520 nm, maximum at 460 nm) used without drapes
N = 34
Outcomes Mean decrease in serum bilirubin after 24 hours of phototherapy
Mean duration of phototherapy
Adverse effects not reported
Notes A third group included in the study used a different phototherapy unit. This group was not included in this review. Study was conducted in Germany
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described in the manuscript
Allocation concealment (selection bias) Unclear risk Not described in the manuscript
Blinding of participants and personnel (performance bias)
All outcomes High risk Participants: neonates by definition blinded, but parents not blinded. Clinicians/Nurses not blinded. The type of intervention may have influenced handling of the baby by parents and healthcare providers
Blinding of outcome assessment (detection bias)
All outcomes Low risk Not reported. We judged bilirubin measurement to be an objective measurement not affected by lack of blinding
Incomplete outcome data (attrition bias)
All outcomes Unclear risk No dropouts reported in the manuscript
Selective reporting (reporting bias) Low risk No protocol available. All expected outcomes and all outcome in the methods reported
Other bias Low risk No other sources of bias identified