Jaafar 2004.

Methods	N=77 Non randomized Fup: na w/o d/o: na
Participants	Eligibility:‐ VL >1,000 copies/ml, CD4>200 cells/mm3, Potent ART >6months ART: NNRTI+NRTI+PI for 59 months; Baseline CD4 483 (200‐919) Baseline VL 4.0 (3.0‐5.5);
Interventions	3 month TI
Outcomes	CD4 decline: 132 cells/mm3; VL rebound: 2.7 log copies/ml,
Notes	Predictors of virological response in a multivariate model: 1.genotypic shift OR 11.68; 2. short time on failing ART OR 3.6; 3. lower HIV RNA Level 2.83; 4. salvage regimen OR 3.69;
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	D ‐ Not used