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| Trial name or title | OPTIMA |
| Methods | |
| Participants | N(proposed)= 1700 |
| Interventions | 3 months ARTDFP ART drug free period compared to non ART drug free periods in a 4 by 4 factorial design |
| Outcomes | primary outcomes=time to AIDS or death secondary outcomes=toxicity, illness, quality of life, CD4, VL, |
| Starting date | June 2001 |
| Contact information | http://www.optimatrial.org/uk/pandp.html |
| Notes | largest trinational trial (UK, USA, Canada) currently ongoing |
