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| Trial name or title | OPTIMA |
| Methods | |
| Participants | 1700 patients randomized to four treatment arms |
| Interventions | Four treatment arms 1. ARTDFP plus standard ART 2. ARTDFP plus MegaART 3.no ARTDFP plus standard ART 4. no ARDFP plus megaART |
| Outcomes | primary outcomes=time to AIDS or death secondary outcomes= toxicity, illness, quality of life, CD4, VL, cost effectiveness |
| Starting date | June 2001 |
| Contact information | tassosl@mindspring.com |
| Notes |
