Table 2 –
Baseline characteristics.
|
Variable |
PAD (n = 10) |
Matched Controls (n = 5) |
P-value (PAD vs Matched Controls) |
Healthy Controls (n = 5) |
P-value (Matched Controls vs Healthy Controls) |
|---|---|---|---|---|---|
| Age (years) | 67.6 (7.6) | 65.6 (7.1) | 0.63 | 34.6 (4.8) | 0.001 |
| Gender male, no (%) | 6 (60) | 4 (80) | 0.44 | 5 (100) | 0.29 |
| BMI (kg/m2) | 30.0 (6.4) | 26.9 (5.2) | 0.36 | 27.1 (4.0) | 0.94 |
| ABI | 0.7 (0.4) | 1.3 (0.1) | 0.003 | N/A | N/A |
| Exercise ABI | 0.6 (0.4) | 1.3 (0.1) | 0.006 | N/A | N/A |
| eGFR (mL/min/1.73 m2) | 79.3 (24.0) | 81.3 (12.4) | 0.86 | N/A | N/A |
| Diabetes, no (%) | 6 (60) | 0 (0) | 0.025 | 0 (0) | - |
| Hypertension, no (%) | 9 (90) | 2 (40) | 0.039 | 0 (0) | 0.11 |
| Current smoker, no (%) | 3 (30) | 0 (0) | 0.20 | 0 (0) | - |
| Claudication, no (%) | 8 (80) | 0 (0) | 0.003 | 0 (0) | - |
| Coronary artery disease, no (%) | 6 (60) | 1 (20) | 0.14 | 0 (0) | 0.29 |
| Hyperlipidemia, no (%) | 8 (80) | 2 (40) | 0.12 | 0 (0) | 0.11 |
| Revascularization history, no (%) | 4 (40) | 0 (0) | 0.099 | 0 (0) | - |
| ACE inhibitor, no (%) | 3 (30) | 0 (0) | 0.17 | 0 (0) | - |
| Beta blocker, no (%) | 3 (30) | 0 (0) | 0.17 | 0 (0) | - |
| Statin, no (%) | 7 (70) | 2 (40) | 0.54 | 0 (0) | 0.11 |
| Anti-coagulation, no (%) | 3 (30) | 1 (20) | 0.49 | 0 (0) | 0.29 |
Values are reported as mean (standard deviation) or as number (percentage). N/A not applicable (not measured).
ABIs are listed for the more symptomatic side. Exercise ABI (n=7).
ABI: Ankle brachial index, ACE: angiotensin-converting enzyme, BMI: body mass index, eGFR: estimated glomerular filtration rate.