Table 3 –

Intra-observer (a) and inter-reader variability of simulated mean signal intensity of a PAD patient (b) and a control (c) for each muscle region (AM, LM, DM, SM, GM) determined by intra-class correlation (ICC) coefficient using a two-way model.

a)
	Intra-observer ICC for AM	Intra-observer ICC for LM	Intra-observer ICC for DM	Intra-observer ICC for SM	Intra-observer ICC for GM
Individual ICC	.999	.998	.998	.995	.999
(95% CI)	.978-1	.966-.999	.964-.999	.922-.999	.995-1
Average ICC	1	.999	.999	.998	1
(95% CI)	.993-1	.989-1	.988-1	.972-1	.998-1
ICC was calculated for each time step, 1 PAD patient (number of targets 500) and for 3 independent calculations with different mesh size in range 0.0005 to 0.0008 m.
b)
	Inter-observer ICC for AM	Inter-observer ICC for LM	Inter-observer ICC for DM	Inter-observer ICC for SM	Inter-observer ICC for GM
Individual ICC	.984	.978	.855	.881	.98
(95% CI)	.982-.985	.976-.979	.844-.865	.872-.89	.979-.982
Average ICC	.992	.989	.922	.937	.99
(95% CI)	.991-.992	.988-.99	.915-.928	.932-.942	.989-.991
ICC was calculated for each time step, 5 cases (number of targets 2479) and for 2 independent raters.
c)
	Inter-observer ICC for AM	Inter-observer ICC for LM	Inter-observer ICC for DM	Inter-observer ICC for SM	Inter-observer ICC for GM
Individual ICC	.988	.972	.915	.873	.927
(95% CI)	.987-.989	.969-.975	.907-.923	.86-.884	.92-.934
Average ICC	.994	.986	.956	.932	.962
(95% CI)	.993-.995	.984-.987	.951-.96	.925-.939	.958-.966
ICC was calculated for each time step, 3 cases (number of targets 1498) and for 2 independent raters. ICC: intra-class correlation; CI: confidence interval.