Table 4.

Reproducibility analysis of the simulated mean signal intensity of controls and PAD patients for each muscle region (AM, LM, DM, SM, GM), as determined by intra-class correlation (ICC) using a two-way model for non-Newtonian and Newtonian models.

a) PAD Patients (n=5)
	Inter-observer ICC for AM	Inter-observer ICC for LM	Inter-observer ICC for DM	Inter-observer ICC for SM	Inter-observer ICC for GM
Individual ICC	0.945	0.993	0.969	0.963	0.992
(95% CI)	0.941–0.950	0.992–0.993	0.967–0.972	0.960–0.966	0.992–0.993
Average ICC	0.972	0.996	0.984	0.981	0.996
(95% CI)	0.970–0.974	0.996–0.997	0.983–0.986	0.980–0.983	0.996–0.996
ICC: intra-class correlation; CI: confidence interval. ICC was calculated for each time step, 5 cases (Number of targets 2479) and for 2 observations.
b) Controls (n=5)
	Inter-observer ICC for AM	Inter-observer ICC for LM	Inter-observer ICC for DM	Inter-observer ICC for SM	Inter-observer ICC for GM
Individual ICC	0.987	0.993	0.880	0.992	0.980
(95% CI)	0.986–0.988	0.992–0.993	0.871–0.888	0.991–0.993	0.978–0.982
Average ICC	0.994	0.996	0.936	0.996	0.990
(95% CI)	0.993–0.994	0.996–0.997	0.931–0.941	0.996–0.996	0.989–0.991
ICC: intra-class correlation; CI: confidence interval. ICC was calculated for each time step, 5 cases (Number of targets 2498) and for 2 observations.