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. 2011 Jul 6;2011(7):CD005198. doi: 10.1002/14651858.CD005198.pub3

Magrath 1976.

Methods Randomised, parallel group, single‐centre trial (Uganda). 
 ITT: unclear. 
 Withdrawals: stated.
Participants Baseline characteristics: screening population: 80; 48 participants randomised (40 evaluated: BCG: 21; control: 19; male:female: BCG 15:6; control: 14:5). 
 Mean age: BCG: 10 years; control: 6 years. 
 Tumour staging: WHO classification. 
 Diagnosis: histopathology.
Entry criteria: untreated BL; remission two weeks after treatment with C.
Interventions BCG versus no treatment. Participants randomised if in remission two weeks after the last dose of C.
Follow‐up: median 1.75 years.
Outcomes Relapse. 
 Overall survival. 
 Event‐free survival. 
 Toxicity.
Notes Participants recruited if in remission. 
 Study type: remittance maintenance.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Said to be "randomised by stage".
Allocation concealment (selection bias) Unclear risk Not stated.
Blinding (performance bias and detection bias) 
 All outcomes High risk Unlikely: therapy involved scarification.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All participants were accounted for.