Olweny 1976.
Methods | Randomised, parallel group, single‐centre trial (Kenya). Withdrawals: stated. | |
Participants | Baseline characteristics: 40 participants randomised.
Mean age: not reported.
Tumour staging: Ziegler and Magrath.
Diagnosis: histopathology. Entry criteria: confirmed BL. |
|
Interventions | C versus COM. Treatment duration was for 2 weeks (or as soon as toxicity abated). A third dose was given to 3 participants in C group and in one participant in COM group. Follow‐up: unclear. |
|
Outcomes | Relapse. Overall survival. Response (remission, reduction in tumour size or no response). | |
Notes | Full text publication. Study type: remission induction. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Stated as "previously prepared random cards". |
Allocation concealment (selection bias) | Low risk | The use of these cards also suggests that this may be adequate. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not described. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Outcomes were reported. |