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. 2020 Jul 5;2020(7):CD009169. doi: 10.1002/14651858.CD009169.pub3

1. Sources of risk of bias*.

Bias domain Source of bias Possible answers
Selection (1) Was the method of randomisation adequate? Yes/No/Unsure
Selection (2) Was the treatment allocation concealed? Yes/No/Unsure
Performance (3) Was the participant blinded to the intervention? Yes/No/Unsure
Performance (4) Was the care provider blinded to the intervention? Yes/No/Unsure
Detection (5) Was the outcome assessor blinded to the intervention? Yes/No/Unsure
Attrition (6) Was the dropout rate described and acceptable? Yes/No/Unsure
Attrition (7) Were all randomised participants analysed in the group to which they had been allocated? Yes/No/Unsure
Reporting (8) Are reports of the study free of the suggestion of selective outcome reporting? Yes/No/Unsure
Selection (9) Were the groups similar at baseline regarding the most important prognostic indicators? Yes/No/Unsure
Performance (10) Were co‐interventions avoided or similar? Yes/No/Unsure
Performance (11) Was the compliance acceptable in all groups? Yes/No/Unsure
Detection (12) Was the timing of the outcome assessment similar in all groups? Yes/No/Unsure
Other (13) Are other sources of potential bias unlikely? Yes/No/Unsure