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. 2020 Jul 23;11(4):791–800. doi: 10.14336/AD.2019.0929

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Copyright: © 2020 Yao et al.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 1. — T value graphs of two independent samples t-test for brain FC between two groups. (A) With the right middle frontal gyrus as the ROI, the FC between the ROI and right insula (peak MNI coordinates: x=38, y=11, z=1) was found to be significantly decreased in the PD + CCPS group. (B) With the left insula as the ROI, the FC between the ROI and bilateral SMA (peak MNI coordinates: left: x=-1, y=-8, z=69; right: x=7, y=-6, z=70) decreased significantly in the PD + CCPS group. (C) With the right insula as the ROI, the FC between the ROI and left middle frontal gyrus (peak MNI coordinates: x=-30, y=40, z=25) decreased significantly in the PD + CCPS group. Color bar indicates the significance levels in the clusters in t values. (p<0.05, TFCE corrected) FC: functional connectivity; ROI: region of interest; SMA: supplementary motor area; MNI: Montreal Neurological Institute.