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Artemisinin attenuated the activation of glial cells, caspase activation and the expression of inflammatory molecules IL-1β in the brain of aged 3xTg mice. (A) Immunofluorescence and Immunohistochemistry of GFAP (Astrocyte marker) and AIF1 (Iba1, microglia marker) (40x). (B) Western blot analysis of the effect of ART on IL-1β and caspase1. (C-D) Quantitation of cleaved caspase1 and IL-1β in B. **p<0.01 3xTg vs WT; #p<0.05 or ##<p: 0.01. 3xTg vs 3xTg+ART.
