Table 2.

Changes in the CSS before and after Treatment (n=149).

	Baseline	Week 2 post-administration	p-value
Total CSS score	11.7 (4.5)	9.3 (5.2)	<0.001
Stool frequency	0.7 (1.0)	0.5 (0.8)	<0.001
Difficulty in evacuation	2.8 (1.3)	2.1 (1.6)	<0.001
A sensation of incomplete evacuation	2.2 (1.6)	1.7 (1.6)	<0.001
Abdominal pain	0.7 (1.3)	0.8 (1.3)	0.237
Time to evacuation	1.2 (1.1)	0.9 (0.9)	<0.001
Assisted bowel movements (laxatives, enemas, or manual maneuvers)	1.5 (0.6)	1.1 (0.8)	<0.001
Number of times/24 hours without bowel movement despite going to the bathroom	0.9 (0.8)	0.7 (0.7)	0.001
Duration (years) of suffering from disturbed defecation	1.6 (1.5)	1.6 (1.4)	―

Data are shown mean (SD).

CSS: constipation scoring system.