Table 1.
Cohort demographics not included during classification.
| Characteristic | Count (Percent) |
|---|---|
| General Demographics | |
| Gender | |
| Male | 172 (86%) |
| Female | 28 (14%) |
| Race | |
| White/Caucasion | 189 (94.5%) |
| African American/Black | 5 (2.5%) |
| Hispanic/Latino | 3 (1.5%) |
| Other | 3 (1.5%) |
| Dysphagia | |
| Pre-Treatment Aspiration | 3 (1.5%) |
| Post-Treatment Aspiration | 19 (9.5%) |
| Post-Treatment Feeding Tube | 22 (11%) |
| Treatment Modality | |
| One Side of Neck | 18 (9%) |
| Both Sides of Neck | 182 (91%) |
| Existing Clinical Covariates* | |
| Smoking* | |
| Never | 94 (47%) |
| Former | 69 (34.5%) |
| Current | 37 (18.5%) |
| T Classification* | |
| T1 | 54 (27%) |
| T2 | 85 (42.5%) |
| T3 | 43 (21.5%) |
| T4 | 18 (9%) |
| N Classification* | |
| 0 | 7 (3.5%) |
| 1 | 25 (12.5%) |
| 2 | 163 (81.5%) |
| 3 | 5 (2.5%) |
| Ajcc 8th Edition* | |
| 1 | 20 (10%) |
| 2 | 103 (51.5%) |
| 3 | 7 (3.5%) |
| 4 | 19 (9.5%) |
| N/A | 51 (25.5%) |
| HPV Status* | |
| Positive | 130 (65%) |
| Negative | 20 (10%) |
| Unknown | 50 (25%) |
| Pathological Grade* | |
| 1 | 1 (0.5%) |
| 2 | 53 (26.5%) |
| 3 | 105 (52.5%) |
| 4 | 2 (1%) |
| N/A | 39 (19.5%) |
| Tumor Subsites* | |
| Base of tongue | 103 (51.5%) |
| Tonsil | 81 (40.5%) |
| NOS | 11 (5.5%) |
| Glossopharyngeal sulcus | 3 (1.5%) |
| Soft Palate | 2 (1%) |
| Therapeutic Combination* | |
| Chemoradiation | 115 (57.5%) |
| Induction Chemotherapy + Chemoradiation | 42 (21%) |
| Radiation Alone | 22 (11%) |
| Induction Chemotherapy + Radiation Alone | 21 (10.5% |
| Tumor Laterality* | |
| Right | 102 (51%) |
| Left | 80 (40%) |
| Bilateral | 18 (9%) |
| Age* | |
| Mean (Range) | 59.4 (37–82) |
| Total Dose To Tumor* | |
| Mean (Range) | 68.5 (60–72) |
| Spatial Features** | |
| Extended oral cavity predicted dose (Gy)** | |
| Mean (Range) | 51.98 (44.87–62.66) |
| Mandible predicted dose (Gy)** | |
| Mean (Range) | 39.5 (32.85–51.95) |
| Medial pterygoid predicted doses (combined) (Gy)** | |
| Mean (Range) | 77.23 (64.86–92) |
| Mandible-tumor minimum Euclidean surface distance (mm)** | |
| Mean (Range) | 4.7 (−1.2–16.33) |
| Medial pharyngeal constrictor-tumor minimum Euclidean surface distance (mm)** | |
| Mean (Range) | 8.43 (−2.06–26.61) |
*
Features considered for the baseline clinical features.
**
Features included in the spatial clustering.