Table 2.

Antibiotic susceptibility of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa as a planktonic population (MIC) and as a biofilm population (MBEC). Adapted from^85–87.

Microorganisms	Staphylococcus aureus			Escherichia coli			Pseudomonas aeruginosa
Strain number	ATCC 2921385,86 ATCC 3555687			ATCC 2592285			ATCC 2785385
Antimicrobial Agents	MIC	MBEC	Ratio	MIC	MBEC	Ratio	MIC	MBEC	Ratio
Oxacillin	0.12–0.25	>1024	>1000
Piperacillin				1 – 4	32	8 – 32	2 – 16	>1024	>64
Aztreonam							2 – 4	>1024	>250
Cefazolin	0.5	>1024	>1000	1 – 4	>1024	>250
Ceftazidime							1 – 2	>1024	>500
Imipenem							1 – 4	>1024	>250
Clindamycin	0.12–0.25	128–256	>1000
Vancomycin	1	>1024(Ref85)	>1000
		>128(Ref86)
		>256(Ref87)
Linezolid	8	>128(Ref86)	>16
Rifampin	<0.02	4(Ref86)	200
Ciprofloxacin	0.25–0.5	512	>1000	0.004 – 0.008	8	>1000	0.25	4	16
Amikacin							2 – 4	16	4 – 8
Gentamicin	0.5	2	4	2 – 4	16	4 – 8	2 – 4	128	32 – 64
Tobramycin				1 – 4	2	2	0.5 – 1	2	2 – 4
Trimethoprim-sulfamethoxazole				0.06 – 0.12	32 – 64	>250
				1.14 – 2.28	608 – 1216	>500

MIC, minimal inhibitory concentration; MBEC minimal biofilm eradication concentration. The unit of the values is μg/mL. Determination of MBEC were established using the MBEC device, formerly called Calgary device, according to the manufacturer’s protocol or with modification of the protocol.