Figure 3. Transcriptome alteration of ECM-receptor and PI3K-AKT pathways by VPS35 D620N.

Specific transcript expression changes (LogFoldChange) for (A) ECM-receptor interaction and (B) PI3K-AKT signaling KEGG pathways from RNA-Seq data are shown. The distribution of all gene perturbations in the pathway are represented in the box plot where the first, median and third quartile are indicated.