Figure 3.

In Utero Microinjection Has Minimal Adverse Effects on Hearing

ABRs of noninjected (wild-type, n = 6), PBS-injected (sham, n = 5), and Anc80L65-injected mice (n = 5). (A) Click-evoked ABRs of wild-type (upper), sham (middle), and Anc80L65-injected (lower) mice at P28. The amplitude of the response is expressed in microvolts (μV). The time is expressed in milliseconds (ms). (B) The ABR was assessed with clicks and with tone bursts at 8 kHz, 16 kHz, and 32 kHz. No significant differences were observed among any of the tested frequencies.