Table 3.
Remission Classification | Intensive Management | Standard Care | Unadjusted |
Adjusted* |
||
---|---|---|---|---|---|---|
Proportion (95% CI) | Proportion (95% CI) | OR (95% CI) | P-value | OR (95% CI) | P-value | |
DAS28-ESR | 32% (25%, 40%) | 18% (12%, 24%) | 2.17 (1.28, 3.68) | 0.004 | 2.38 (1.36,4.17) | 0.002 |
DAS28-CRP | 21% (15%, 27%) | 10% (5%, 15%) | 2.44 (1.27, 4.70) | 0.008 | 2.52 (1.28,4.99) | 0.008 |
SDAI | 17% (11%, 23%) | 10% (6%, 15%) | 1.81 (0.94, 3.47) | 0.074 | 1.90 (0.97,3.72) | 0.060 |
CDAI | 18% (12%, 24%) | 10% (6%, 15%) | 1.92 (1.00, 3.68) | 0.049 | 2.10 (1.07,4.09) | 0.030 |
ACR/EULAR Boolean | 13% (8%, 18%) | 6% (2%, 10%) | 2.32 (1.04, 5.18) | 0.040 | 2.44 (1.06,5.64) | 0.036 |
Adjusted for demographics (age, gender, ethnicity, disease duration), design factors (NHS region) and baseline values; ACR/EULAR Boolean remissions were only adjusted for demographics; standard of care arm was the reference group; OR = odds ratio; CI = confidence intervals.