Table 3.
Association between knee OA and pain-related traits and two IL15RA SNPs.
| Trait | IL15RA SNP | |
|---|---|---|
| rs2228059 (effect allele = C) | rs7097780 (effect allele = G) | |
| Radiographic severity: K/L grade 2 vs. grades 3 + 4 | OR = 0.98 (0.75–1.27) | OR = 1.19 (0.90–1.57) |
| Symptomatic vs. asymptomatic knee OA | OR = 1.02 (0.76–1.36) | OR = 1.48 (1.10–1.98), p = 0.0098 |
| Neuropathic pain post-TJR | OR = 0.76 (0.63–0.92), p = 0.005 | OR = 0.94 (0.76–1.15) |
Odds ratios (OR) are adjusted for age, sex, and BMI. Bold values indicate statistically significant results (p < 0.01).