Table 2.
Results of the univariate analysis of associations of economic and socioeconomic factors with outcome.
| TRM (2y) (%, 95%CI) | OS (2y) (%, 95%CI) | PI (2y) (%, 95%CI) | PFS (2y) (%, 95%CI) | Overall cGvHD (2y) (%, 95%CI) | Extensive cGvHD (2y) (%, 95%CI) | ||
|---|---|---|---|---|---|---|---|
| HCE current | ≤ median | 61 (56–66) | 23 (18–28) | 17 (13–22) | 22 (17–27) | 27 (21–32) | 17 (13–22) |
| > median | 55 (53–57) | 32 (30–33) | 16 (14–17) | 29 (28–31) | 37 (35–39) | 24 (22–25) | |
| p-value | 0.04 | 0.002 | 0.69 | 0.013 | 0.002 | 0.01 | |
| HCE as % of GDP | ≤ median | 60 (56–63) | 25 (22–29) | 17 (15–20) | 23 (20–27) | 27 (23–30) | 18 (15–21) |
| > median | 54 (53–56) | 32 (31–34) | 15 (14–17) | 30 (29–32) | 39 (37–40) | 24 (23–26) | |
| p-value | 0.003 | <0.001 | 0.17 | <0.001 | <0.001 | <0.001 | |
| HCE private | ≤ median | 58 (54–62) | 27 (24–31) | 15 (13–18) | 26 (23–30) | 35 (31–39) | 21 (18–25) |
| > median | 55 (53–57) | 32 (30–33) | 16 (15–17) | 29 (28–31) | 36 (35–38) | 23 (22–25) | |
| p-value | 0.51 | 0.26 | 0.73 | 0.76 | 1.0 | 0.25 | |
| HDI | ≤ median | 59 (55–63) | 25 (22–29) | 18 (15–21) | 23 (19–27) | 27 (23–31) | 17 (14–21) |
| > median | 55 (53–56) | 32 (31–34) | 15 (14–17) | 30 (28–32) | 38 (36–40) | 24 (22–26) | |
| p-value | 0.019 | <0.001 | 0.31 | 0.001 | <0.001 | <0.001 | |
| Team density per population | ≤ median | 58 (54–63) | 28 (23–32) | 15 (12–18) | 27 (23–31) | 37 (32–42) | 23 (18–27) |
| > median | 55 (53–57) | 31 (30–33) | 16 (15–17) | 29 (27–31) | 36 (34–38) | 23 (21–25) | |
| p-value | 0.33 | 0.14 | 0.85 | 0.4 | 0.70 | 0.38 | |
| Team density per area | ≤ median | 55 (50–60) | 31 (27–35) | 16 (13–19) | 29 (25–34) | 38 (33–43) | 24 (19–28) |
| > median | 56 (54–57) | 31 (29–33) | 16 (14–17) | 29 (27–30) | 36 (34–38) | 23 (21–24) | |
| p-value | 0.72 | 0.93 | 0.96 | 0.67 | 0.62 | 0.44 | |
| No. alloHCT* (team activity) | ≤ median | 58 (55–61) | 29 (26–32) | 14 (12–16) | 28 (25–31) | 37 (34–41) | 23 (20–26) |
| > median | 55 (53–57) | 32 (30–34) | 16 (15–18) | 29 (27–31) | 36 (34–38) | 23 (21–25) | |
| p-value | 0.04 | 0.13 | 0.06 | 0.58 | 0.12 | 0.77 |
HCE indicates health care expenditure; GDP, gross domestic product per capita; HDI, human development index; TRM, transplant-related mortality; OS, overall survival; PI, progression incidence; PFS, progression-free survival; cGvHD, chronic graft-vs.-host disease; CI, confidence interval.
*
Refers to transplantation procedures according to selection criteria chosen for this study preformed between 2011 and 2015.