Table 2.
Prognostic value of LBP with different clinicopathological factors in the LIHC cohort of TCGA from Kaplan-Meier plotter database.
| OS (n = 364) | RFS (n = 316) | ||||||
|---|---|---|---|---|---|---|---|
| Patient number | P-value | HR [95% CI] | Patient number | P-value | HR [95% CI] | ||
| Pathology | |||||||
| Stage | |||||||
| 1 + 2 | 253 | 0.0062 | 3.2 (1.33–7.69) | 227 | 0.4262 | 1.2 (0.77–1.88) | |
| 3 + 4 | 87 | 0.0573 | 0.56 (0.31–1.03) | 68 | |||
| Grade | |||||||
| 1 | 55 | 45 | |||||
| 2 | 174 | 0.0981 | 1.57 (0.92–2.68) | 147 | 0.3715 | 1.25 (0.77–2.03) | |
| 3 | 118 | 0.104 | 1.65 (0.9–3.02) | 106 | 0.1012 | 0.63 (0.37–1.1) | |
| 4 | 12 | ||||||
| AJCC_T | |||||||
| 1 | 180 | 0.024 | 1.97 (1.08–3.58) | 160 | 0.3479 | 1.31 (0.75–2.29) | |
| 2 | 90 | 0.0288 | 0.44 (0.21–0.94) | 79 | |||
| 3 | 78 | 65 | |||||
| 4 | 13 | 6 | |||||
| Vascular invasion | |||||||
| None | 203 | 0.1673 | 1.43 (0.86–2.4) | 175 | 0.1106 | 1.49 (0.91–2.45) | |
| Micro | 90 | 0.0451 | 2.37 (0.99–5.64) | 81 | 0.3381 | 0.72 (0.36–1.42) | |
| Macro | 16 | 14 | |||||
| Patient | |||||||
| Gender | |||||||
| Male | 246 | 0.124 | 1.42 (0.91–2.21) | 208 | 0.044 | 0.64 (0.41–0.99) | |
| Female | 118 | 0.0925 | 0.6 (0.33–1.09) | 105 | 0.2189 | 1.47 (0.79–2.75) | |
| Race | |||||||
| White | 181 | 0.216 | 0.72 (0.43–1.21) | 147 | 0.1142 | 0.67 (0.41–1.1) | |
| Black or African American | 17 | 13 | |||||
| Asian | 155 | 0.0508 | 1.83 (0.99–3.38) | 143 | 0.1677 | 0.69 (0.4–1.17) | |
| Sorafenib treatment | |||||||
| Treated | 30 | 22 | |||||
| Risk factors | |||||||
| Alcohol consumption | |||||||
| Yes | 115 | 0.1001 | 0.57 (0.29–1.12) | 98 | 0.1184 | 0.61 (0.32–1.14) | |
| No | 202 | 0.0332 | 1.65 (1.04–2.62) | 183 | 0.2877 | 0.77 (0.47–1.25) | |
| Hepatitis virus | |||||||
| Yes | 150 | 0.005 | 2.45 (1.28–4.67) | 138 | 0.2678 | 0.74 (0.44–1.26) | |
| No | 167 | 0.0066 | 0.52 (0.32–0.84) | 143 | 0.1187 | 0.66 (0.39–1.12) | |
Cohorts patients only more than 80 were analyzed further.