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. 2020 Jul 23;13:118. doi: 10.3389/fnmol.2020.00118

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Copyright © 2020 Arreguin and Colognato.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Laminin α2 in the ventricular-subventricular zone (VZ-SVZ) neural stem cell (NSC) niche. (A) Laminin α2 influences NSC proliferation and differentiation. It influences neurogenesis and gliogenesis in the VZ-SVZ, as well as the proliferation and survival of progenitors for midbrain dopaminergic neurons. (B) Oligodendrogenesis and myelination are influenced by LAMA2 expression. In particular, LAMA2 expression influences the survival and differentiation of oligodendrocyte precursor cells (OPCs) as well as the maturation of oligodendrocytes.