TABLE 2.

Pathway analysis of metabolites from C10-treated vs CTR cells.

Pathway name	Match status	p-value	Impact
Purine metabolism	1/65	1.7051E-5	0.0
Pyrimidine metabolism	1/39	1.7051E-5	0.0
D-Glutamine and D-glutamate metabolism	3/6	3.6167E-4	0.5
Aminoacyl-tRNA biosynthesis	6/48	8.2099E-4	0.0
Starch and sucrose metabolism	1/18	0.0020341	0.4207
Galactose metabolism	1/27	0.0020341	0.03499
Neomycin, kanamycin and gentamicin biosynthesis	1/2	0.0020341	0.0
Nitrogen metabolism	2/6	0.0024727	0.0
Alanine, aspartate and glutamate metabolism	10/28	0.012493	0.67629
Glyoxylate and dicarboxylate metabolism	7/32	0.015648	0.13493
Arginine biosynthesis	5/14	0.022856	0.11675
Propanoate metabolism	3/23	0.026032	0.04061
Citric acid cycle	7/20	0.032615	0.41976
Pyruvate metabolism	5/22	0.039236	0.2395

Pathways involved in C-10 treated cells with the number of metabolites that match in the indicated pathway; p is the original p-value calculated from the Enrichment Analysis; impact is the pathway impact value calculated from pathway topology analysis.