TABLE 2.

Bioprocess features selected by each surrogate modeling technique from Feature Set 2 (X = selected).

Feature	FS2-RF	FS2-GPR	FS2-MARS
Average DO concentration d0	X
Average DO concentration dd0	X
Average DO concentration dd2			X
Average DO concentration dd4	X
Average DO concentration gradient d0	X
Average DO concentration gradient dd2	X	X
Average DO concentration gradient dd4	X		X
Average DO concentration gradient dd5	X
d1 average pH gradient			X
dd0 aggregate size			X
dd0 cell density			X
dd0–dd1 cell density gradient		X
dd1 average pH	X		X
dd1 average acceleration of cell density normalized DO gradient	X
dd2 aggregate size	X
dd2 average acceleration of DO gradient		X
dd2 average pH			X
dd2 average pH gradient	X
dd2 average acceleration of cell density normalized DO gradient	X
dd2–dd3 aggregate size gradient	X
dd3–dd5 cell density gradient			X
dd4 average pH gradient		X
dd5 average acceleration of cell density normalized DO gradient	X	X
Cell density normalized DO concentration dd1	X
Average cell density normalized DO concentration gradient dd5		X
IWP2 treatment time [h]		X	X
Overall aggregate size gradient	X
Overall density gradient			X