Table 4.
Intra-laboratory variation for potency estimates of study samples in the VaccZyme, Vi poly-l-lysine and biotinylated-Vi ELISAs.
ELISA | Laboratory code | Intra-laboratory variation for study samples as % GCVa |
|||||||
---|---|---|---|---|---|---|---|---|---|
10/126 | G | Hb | I | J | K | L | M | ||
Vi poly-l-lysine | 1 | 5 | 6 | 6 | 9 | 7 | 9 | 6 | 9 |
2 | 18 | 15 | 12 | 6 | 20 | 22 | 16 | 23 | |
3 | 6 | 10 | ntc | 12 | 8 | ncd | 8 | 7 | |
4 | 22 | 27 | 9 | 12 | ncd | 42 | 44 | ncd | |
5 | 12 | 27 | 10 | 11 | 16 | ncd | 28 | 10 | |
6 | 9 | 8 | 11 | 21 | 9 | 15 | 25 | 2 | |
7 | 12 | 25 | 22 | 51 | 29 | ncd | 47 | 22 | |
8 | 5 | 10 | 12 | 3 | 6 | 5 | 8 | 6 | |
9 | 17 | 12 | 12 | 10 | 14 | 10 | 13 | 13 | |
10 | 7 | 8 | 10 | 16 | 11 | ncd | 17 | 2 | |
VaccZyme | 1 | 10 | 9 | 8 | 10 | 8 | 7 | 8 | 6 |
5 | 18 | 14 | 2 | 5 | 25 | 59 | 41 | 32 | |
6 | 5 | 6 | 3 | 5 | 2 | 2 | 5 | 5 | |
Biotinylated-Vi | 6 | 5 | 5 | 2 | 7 | 8 | 2 | 4 | 4 |
Geometric Coefficient of Variation.
Coded duplicate of IS 16/138.
Not tested.
Not calculated as fewer than 3 valid potency estimates were obtained for the sample.