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. 2020 Jul 23;11:712. doi: 10.3389/fgene.2020.00712

TABLE 1.

Patient’s demographic and clinical characteristics in the two study groups depicted as percentages of respective categories or mean ± standard deviation (LC and HCC).

Variable LC HCC p-Value
Age > 60 years 36.84% 68.75% 0.003
Male 55.26% 56.25% 0.92
HVC etiology 38.89% 52.08% 0.23
HBV etiology 33.33% 33.33% 1
HDV etiology 25% 8.33% 0.07
INR 1.5 ± 0.49 1.12 ± 0.18 <0.0001
Tbil (mg/dl) 2.99 ± 3.13 0.83 ± 0.58 <0.0001
Serum creatinine (mg/dl) 0.88 ± 0.24 0.97 ± 0.31 0.29
Serum albumin (g/dl) 3.34 ± 0.79 3.67 ± 0.72 0.06
MELD score 14.02 ± 5.09 8.83 ± 2.83 <0.0001
Ascites 31.11% 6.25% 0.001
Child Pugh class A 52.63% 91.67%
Child Pugh class B 28.95% 8.33%
Child Pugh class C 18.42% 0% 0.0001
Serum AFP (ng/ml) 10.52 ± 18.15 200.55 ± 380.29 0.001
miR-21-5p relative expression 15.17 ± 19.29 47.96 ± 71.31 0.017
miR-92a-3p relative expression 1.24 ± 1.18 0.61 ± 0.99 0.0005

HBV, hepatitis B virus; HCV, hepatitis C virus; HDV, hepatitis D virus; INR, international normalized ratio; Tbil, total bilirubin; MELD score, model for end-stage liver disease score; AFP, alpha-fetoprotein.