Table 3.
EORTC QLQ-C30 functional and symptom scales at T0 and T1 compared to the pooled European normative data [28].
| EORTC QLQ-C30 | Mean (SD) p value T0 N = 17 |
Range | Mean (SD) p value T1 N = 15 |
Range | European mean (SD) N = 15386 |
|---|---|---|---|---|---|
| Function scales | |||||
| Physical | 84.3 (15.3) p = 0.83 |
[47-100] | 80.9 (16.3) p = 0.33 |
[53-100] | 85.1 (18.9) |
| Role | 85.3 (21.2) p = 0.85 |
[33-100] | 81.1 (18.7) p = 0.52 |
[50-100] | 84.3 (24.6) |
| Emotional | 79.9 (29.0) p = 0.43 |
[0-100] | 80.0 (17.5) p = 0.22 |
[50-100] | 74.2 (24.7) |
| Cognitive | 72.6 (27.6) p = 0.09 |
[0-100] | 64.4 (25.9) p = 0.009 d = 0.79 |
[17-100] | 84.8 (21.3) |
| Social | 85.3 (21.2) p = 0.86 |
[33-100] | 77.8 (25.7) p = 0.23 |
[33-100] | 86.2 (24.1) |
| Global QOL | 76.0 (17.4) p = 0.03 d = 0.47 |
[50-100] | 72.2 (22.9) p = 0.33 |
[42-100] | 66.1 (21.7) |
|
| |||||
| Symptom scales/items | |||||
| Fatigue | 27.5 (25.8) p = 0.75 |
[0-78] | 21.5 (20.4) p = 0.15 |
[0-67] | 29.5 (25.5) |
| Nausea/vomiting | 2.0 (5.5) p = 0.01 d = 0.59 |
[0-17] | 5.6 (15.0) p = 0.93 |
[0-50] | 5.9 (16.0) |
| Pain | 12.7 (16.2) p = 0.01 d = 0.57 |
[0-33] | 18.9 (23.5) p = 0.46 |
[0-67] | 23.5 (27.1) |
| Dyspnea | 13.7 (29.0) p = 0.76 |
[0-100] | 15.6 (24.8) p = 0.96 |
[0-67] | 15.9 (24.6) |
| Insomnia | 11.8 (16.4) p = 0.002 d = 0.68 |
[0-33] | 13.3 (21.1) p = 0.03 d = 0.63 |
[0-67] | 26.6 (30.3) |
| Appetite loss | 7.8 (18.7) p = 0.64 |
[0-67] | 15.6 (33.0) p = 0.53 |
[0-100] | 10.0 (21.6) |
| Constipation | 5.9 (17.6) p = 0.14 |
[0-67] | 9.0 (23.4) p = 0.57 |
[0-67] | 12.5 (23.3) |
| Diarrhea | 11.8 (20.2) p = 0.65 |
[0-67] | 6.7 (13.8) p = 0.45 |
[0-33] | 9.5 (20.9) |
| Financial difficulties | 13.7 (33.5) p = 0.71 |
[0-100] | 13.4 (24.7) p = 0.67 |
[0-67] | 10.6 (23.6) |
Bilateral one sample t-tests have been conducted to compare the means with the normative data of the pooled European normative data. d = Cohen′s d effect size (0.2 = small effect, 0.5 = medium effect, and 0.8 = large effect). Functional scales: a lower score compared to the European mean indicates a worse functioning. Symptom scales: a higher score compared to the European mean indicates more symptoms.