Table 4.
Descriptive statistics of anxiety, depression, fatigue, subjective and objective cognitive impairment, and number of patients impaired.
|
T
0
N = 17 |
T
1
N = 15 |
|
|---|---|---|
| Anxiety and depression | ||
| HADS anxiety (mean, SD) | 5.8 (6.0) | 6.4 (6.4) |
| HADS depression (mean, SD) | 5.5 (3.4) | 5.4 (4.7) |
| Number of patients (%) with elevated A scores (≥8) | 6 (35%) | 6 (40%) |
| Number of patients (%) with elevated D scores (≥8) | 7 (41%) | 4 (27%) |
| Number of patients (%) with elevated A and D scores (≥8) | 5 (30%) | 4 (27%) |
| Fatigue | ||
| FSS (mean, SD) | 3.0 (1.8) | 3.1 (1.5) |
| Number of patients (%) with elevated scores (≥4) | 7 (41%) | 7 (47%) |
| Subjective cognition | ||
| CFQ (mean, SD) | 39.8 (23.1) | 40.7 (23.7) |
| Number of patients (%) with elevated scores (≥44) | 7 (41%) | 7 (47%) |
|
| ||
| Cognitive computerized test results for processing speed, memory, and executive function composites |
T
0
N = 16^^ Mean (SD) |
T
1
N = 12^^ Mean (SD) |
| Processing speed composite | -0.67 (1.00) | -1.20 (0.98) |
| Memory composite | -0.23 (0.97) | 0.03 (0.83) |
| Executive function composite | -0.31 (0.79) | -0.30 (0.90) |
| Number (%) of patients impaired on objective computerized testing^ | 7 (44%) | 4 (33%) |
^Cognitive impairment was defined when abnormal performance (z ≤ -1.00) occurred on at least 3 tests of the 7 in the battery. ^^For, respectively, 1 at T0 and 4 patients at 1-year follow-up, no assessment was available.