Table 1.
Literature review of clinical cases involving metastasis of systemic malignancy into a pituitary adenoma.
| Cancer | Age | Gender | Pituitary tumor | Presentation | Radiation? | Post-op survival | |
|---|---|---|---|---|---|---|---|
| Lung cancer | Sogani et al. 2014 [6] | 64 | M | Nonfunctioning | Vision loss | Yes | Not reported |
| Hoellig et al. 2009 [7] | 71 | M | Nonfunctioning | Vision loss | No | 13 days | |
| Rotondo et al. 2013 [8] | 66 | M | Prolactin | Headache | No | No surgery | |
| Molinatti et al. 1985 [9] | 71 | M | LH/FSH | Vision loss | Yes | 1 month | |
| Post et al. 1988 [10] | 77 | M | Nonfunctioning | Vision loss | Yes | 6 months | |
| Kovacs, 1973 [11] | N/A | N/A | N/A | N/A | N/A | N/A | |
| Scheithauer, 1984 [12] | N/A | N/A | N/A | N/A | N/A | N/A | |
| Hanna et al. 1999 [13] | 42 | F | Prolactin | Headache | Not reported | Not reported | |
| Nasr et al. 2006 [14] | 44 | F | Growth hormone | Vision loss/acromegaly | Yes | >3 months | |
| Fujimori et al. 2014 [15] | 80 | M | Not reported | Vision loss/CN 3 palsies | Yes | Not reported | |
| Renal cancer | James et al. 1984 [16] | 75 | M | Nonfunctioning | Vision loss | Yes | Not reported |
| Koutourousiou et al. 2010 [17] | 42 | F | ACTH | Cushing's syndrome | Not reported | >55 months | |
| Koutourousiou et al. 2010 [17] | 76 | M | Nonfunctioning | Panhypopituitarism | Not reported | >27 months | |
| Weber et al. 2003 [18] | 62 | F | Nonfunctioning | Vision loss | Not reported | 8 months | |
| Burns et al. 1973 [19] | 78 | M | Nonfunctioning | Fever | Not reported | No surgery | |
| Magnoli et al. 2014 [20] | 76 | F | FSH/LH | Vision loss, CN 3 palsies | No | 24 months | |
| Breast cancer | Bret et al. 2001 [21] | 75 | F | FSH/LH | Vision loss | No | >18 months |
| Richardson and Katayama, 1971 [22] | 70 | F | Nonfunctioning | Headache/L hemiparesis | Yes | 4 months | |
| van der Zwan et al. 1971 [23] | 73 | F | Nonfunctioning | Vision loss | No | 1 month | |
| Zager et al. 1987 [24] | 56 | F | Nonfunctioning | CN 6 palsies | Yes | No surgery | |
| Mills et al. 2018 [25] | 65 | F | FSH/LH | Apoplexy | No | 12 days | |
| Idiopathic | Nassiri et al. 2012 [26] | 55 | F | Growth hormone | Acromegaly | Yes | 5 months |
| Bret et al. 2001 [21] | 87 | F | FSH/LH | Vision loss | No | >6 months | |
| Hurley et al. 1992 [27] | 76 | M | Growth hormone | Vision loss/acromegaly | No | 6 months | |
| Post et al. 1988 [10] | 61 | F | ACTH | Vision loss | Yes | Not reported | |
| Colon | Noga et al. 2001 [28] | 60 | M | Nonfunctioning | Vision loss | No | “Shortly” |
| Skulsampaopol et al. 2017 [29] | 53 | M | Nonfunctioning | Vision loss | Yes | 3 months | |
| Thewjitcharoen et al. 2014 [30] | 65 | M | Prolactin | Vision loss | No | 9 months | |
| Stomach | Van Seters et al. 1985 [31] | 66 | F | Prolactin | Vision loss | No | 12 days |
| Molinatti et al. 1985 [9] | 66 | F | Prolactin/growth hormone | Vision loss | No | 2 days | |
| Prostate | Ramsay et al. 1988 [32] | 57 | M | Nonfunctioning | Incidental | Yes | No surgery |
| Pancreas | Ramsay et al. 1988 [32] | 50 | F | ACTH | Cushing's syndrome | Yes | No surgery |
| Mediastinum | Abe et al. 1997 [33] | 46 | F | Prolactin | Vision loss | No | 6 months |
| Melanoma | Yang et al. 2017 [34] | 62 | F | Prolactin | Vision loss | No | >22 months |