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Classification of the response based on depth of response
| MRD response criteria | Abbreviation | Level of reduction |
|---|---|---|
| MRD grade 3 | MRD3 | Nonclonal plasma cells or clonotypes between 10−3 and 10−4 |
| MRD grade 4 | MRD4 | Nonclonal plasma cells or clonotypes between 10−4 and 10−5 |
| MRD grade 5 | MRD5 | Nonclonal plasma cells or clonotypes between 10−5 and 10−6 |
| MRD grade 6 | MRD6 | Nonclonal plasma cells or clonotypes <10−6 |
