Table 3.

Predicators of OS and PFS

Outcome and variable	Univariate analysis OR (95% CI)	Multivariate analysis OR (95% CI)	Multivariate analysis P
Cohort 1
OS
MTV manual, high vs low	0.25 (0.10-0.66)	0.20 (0.07-0.57)	.002
Bridging therapy, yes vs no	1.00 (0.38-2.58)	1.02 (0.39-2.69)	.95
LDH before conditioning >2×ULN vs <2×ULN	1.45 (0.56-3.73)	0.60 (0.21-1.68)	.33
PFS
MTV manual, high vs low	0.40 (0.18-0.89)	0.30 (0.12-0.72)	.007
Bridging therapy, yes vs no	0.72 (0.30-1.70)	0.78 (0.32-1.87)	.58
LDH before conditioning >2×ULN vs <2×ULN	1.04 (0.42-2.60)	0.51 (0.18-1.43)	.20
Cohort 2
OS
MTV manual, high vs low	0.14 (0.05-0.42)	0.18 (0.04-0.69)	.01
Bridging therapy, yes vs no	2.99 (0.85-10.43)	0.77 (0.15-3.84)	.75
LDH before conditioning >2×ULN vs <2×ULN	5.86 (2.18-15.71)	3.17 (1.07-9.40)	.03
PFS
MTV manual, high vs low	0.29 (0.12-0.69)	0.34 (0.12-0.96)	.04
Bridging therapy, yes vs no	2.00 (0.78-5.14)	0.93 (0.29-2.93)	.93
LDH before conditioning >2×ULN vs <2×ULN	4.22 (1.59-11.22)	3.18 (1.09-9.31)	.03