Table 3. Variables Associated With Parathyroid Hormone Testing in Patients With Kidney Stones and Hypercalcemia.
| Variable | OR (95% CI) | P value |
|---|---|---|
| Age per 10 y | 0.95 (0.90-1.00) | .03 |
| Male sex | 1.00 (0.77-1.29) | .98 |
| Index stone diagnosis (surgical procedure vs inpatient or outpatient) | 0.47 (0.40-0.56) | <.001 |
| Osteoporosis | 1.22 (0.93-1.61) | .16 |
| Metastatic cancer | 0.63 (0.49-0.81) | <.001 |
| eGFR, mL/min/1.73 m2 | ||
| >60 | 1 [Reference] | <.001 |
| 45-60 | 1.10 (0.92-1.30) | |
| <45 | 1.52 (1.31-1.78) | |
| Albumin-corrected vs measured hypercalcemia | 0.32 (0.28-0.37) | <.001 |
| Calcium concentration elevation >10.5 per 0.1 mg/dL | 1.07 (1.05-1.08) | <.001 |
| No. of calcium concentration measurements >10.5 mg/dL | 1.08 (1.06-1.10) | <.001 |
| Thiazide or thiazide-type medications | 1.05 (0.92-1.20) | .46 |
| Region | ||
| Southeast | 1 [Reference] | <.001 |
| Midwest | 1.05 (0.90-1.22) | |
| Northeast | 1.37 (1.17-1.61) | |
| West | 1.23 (1.03-1.47) | |
| Stone specialty care | ||
| Neither | 1 [Reference] | <.001 |
| Nephrologist or urologist | 1.56 (1.35-1.81) | |
| Both | 6.57 (5.33-8.10) | |
| Endocrine care | ||
| None | 1 [Reference] | <.001 |
| Endocrinologist | 4.93 (4.11-5.93) |
Abbreviations: eGFR, estimated glomerular filtration rate; OR, odds ratio.
SI conversion factors: To convert serum calcium concentration to millimoles per liter, multiply by 0.25.