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. 2020 Jul 11;11(18):5478–5489. doi: 10.7150/jca.46145

Figure 1.

Figure 1

The development and application of patient-derived xenograft (PDX) models. F1: Cancer tissues are engrafted directly into immuno-deficient mice. F2: Then cancers are transplanted into a second generation of immuno-deficient mice.