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. 2020 Jul 14;11(18):5527–5535. doi: 10.7150/jca.46563

Table 2.

Univariate and multivariate logistic regression for analyzing the risk factors for early death in the SEER database

Variables Univariate Multivariate
OR 95%CI p value OR 95%CI p value
Age (years)
<40 Ref Ref
40-59 1.087 0.815-1.463 0.575 0.836 0.603-1.168 0.286
60-79 1.513 1.143-2.023 0.004 1.106 0.799-1.545 0.548
80+ 3.496 2.549-4.836 <0.001 1.458 0.993-2.152 0.056
Sex
Male Ref Ref
Female 1.021 0.899-1.159 0.748 0.828 0.704-0.973 0.022
Race
White Ref Ref
Black 1.091 0.906-1.311 0.356 0.910 0.727-1.137 0.410
Other 0.834 0.695-0.998 0.049 0.706 0.569-0.874 0.001
Marital status
Married Ref Ref
Separated/Divorced 0.049 1.090-1.623 0.005 1.305 1.034-1.642 0.024
Widowed 2.243 1.842-2.732 <0.001 1.241 0.963-1.598 0.094
Single 1.405 1.195-1.651 <0.001 1.273 1.047-1.547 0.015
Primary site
Cardiac/fundus Ref Ref
Body 1.103 0.888-1.367 0.371 1.201 0.921-1.561 0.174
Antrum/pylorus 1.308 1.091-1.565 0.004 1.305 1.036-1.644 0.023
Lesser& greater curvature 1.184 0.999-1.401 0.051 1.314 1.064-1.620 0.011
Other 1.464 1.222-1.752 <0.001 1.148 0.919-1.435 0.223
Histology
Adenocarcinoma Ref Ref
Signet ring cell carcinoma 0.893 0.778-1.024 0.107 0.999 0.831-1.201 0.996
Grade
Well/moderately Ref Ref
Poorly /undifferentiated 1.321 1.144-1.528 <0.001 1.904 1.588-2.287 <0.001
Bone metastases
Yes Ref Ref
No/unknown 0.752 0.632-0.895 0.001 0.64 0.521-0.786 <0.001
Brain metastases
Yes Ref Ref
No/unknown 0.401 0.264-0.603 <0.001 0.328 0.202-0.529 <0.001
Liver metastases
Yes Ref Ref
No/unknown 0.815 0.722-0.921 0.001 0.798 0.682-0.934 0.005
Lung metastases
Yes Ref Ref
No/unknown 0.746 0.631-0.884 0.001 0.749 0.614-0.915 0.004
T stage
T1 Ref Ref
T2 0.589 0.413-0.830 0.003 0.591 0.391-0.883 0.011
T3 0.657 0.530-0.814 <0.001 0.928 0.719-1.197 0.566
T4 0.938 0.774-1.136 0.512 1.121 0.887-1.418 0.341
Unknown 1.181 0.996-1.400 0.056 1.051 0.858-1.289 0.630
N stage
N0 Ref Ref
N1 0.710 0.615-0.820 <0.001 0.821 0.692-0.973 0.023
N2 0.476 0.357-0.630 <0.001 0.703 0.500-0.982 0.041
N3 0.530 0.400-0.695 <0.001 0.783 0.553-1.102 0.164
Unknown 1.344 1.125-1.607 0.001 1.245 1.005-1.542 0.045
Surgery
Yes Ref Ref
No/unknown 2.269 1.809-2.870 <0.001 2.697 1.993-3.675 <0.001
Radiation
Yes Ref Ref
No/unknown 1.229 1.053-1.437 0.009 0.985 0.815-1.193 0.879
Chemotherapy
Yes Ref Ref
No/unknown 8.187 7.125-9.422 <0.001 8.53 7.308-9.978 <0.001