Table 2.
MiRNAs Differentially Expressed in LSCC Patients (n = 6) Relative to the HCs (n = 6) Following RNA-seq (P < 0.05; | log2 fold-change | ≥ 0.5)
| miRNA | LSCC_Ex_readcount | HC_Ex_readcount | log2FoldChange | P-value |
|---|---|---|---|---|
| Upregulated miRNA | ||||
| hsa-miR-1246 | 392.891 | 122.970 | 1.400 | 0.000 |
| hsa-miR-27a-5p | 299.030 | 122.568 | 1.127 | 0.001 |
| hsa-miR-1291 | 37.767 | 10.102 | 1.398 | 0.001 |
| hsa-miR-574-5p | 61.804 | 25.432 | 1.109 | 0.002 |
| hsa-miR-196a-5p | 235.302 | 48.010 | 1.443 | 0.003 |
| hsa-miR-365a-5p | 13.963 | 2.770 | 1.423 | 0.003 |
| hsa-miR-7704 | 18.263 | 4.184 | 1.354 | 0.003 |
| hsa-miR-522-3p | 15.708 | 2.740 | 1.357 | 0.006 |
| hsa-miR-767-5p | 2.409 | 0.000 | 1.302 | 0.006 |
| hsa-miR-4677-5p | 2.954 | 0.585 | 1.271 | 0.010 |
| hsa-miR-452-5p | 101.282 | 55.955 | 0.768 | 0.012 |
| hsa-miR-556-5p | 12.751 | 4.314 | 1.094 | 0.015 |
| hsa-miR-105-5p | 11.412 | 1.996 | 1.204 | 0.015 |
| hsa-miR-548ah-3p | 27.558 | 12.547 | 0.909 | 0.017 |
| hsa-miR-548p | 27.558 | 12.745 | 0.892 | 0.018 |
| hsa-miR-487b-5p | 2.360 | 0.099 | 1.122 | 0.019 |
| hsa-miR-203a-3p | 40.489 | 21.240 | 0.783 | 0.020 |
| hsa-miR-203b-5p | 40.489 | 21.240 | 0.783 | 0.020 |
| hsa-miR-3128 | 2.148 | 0.487 | 1.099 | 0.027 |
| hsa-miR-551a | 6.673 | 2.561 | 1.020 | 0.027 |
| hsa-miR-1-3p | 1564.803 | 692.038 | 0.911 | 0.028 |
| hsa-miR-552-3p | 5.304 | 1.311 | 1.059 | 0.033 |
| hsa-miR-4654 | 3.021 | 0.446 | 1.030 | 0.036 |
| hsa-miR-1185-2-3p | 4.428 | 1.506 | 1.005 | 0.039 |
| hsa-miR-2277-5p | 4.042 | 1.080 | 0.987 | 0.040 |
| hsa-miR-7-5p | 4353.305 | 2404.923 | 0.727 | 0.041 |
| hsa-miR-3529-3p | 4290.922 | 2395.239 | 0.715 | 0.043 |
| hsa-miR-941 | 994.324 | 478.947 | 0.822 | 0.045 |
| hsa-miR-125b-1-3p | 23.944 | 9.010 | 0.940 | 0.046 |
| hsa-miR-24-3p | 17884.990 | 12406.933 | 0.492 | 0.050 |
| novel_259 | 2.369 | 0.198 | 0.938 | 0.050 |
| novel_428 | 2.369 | 0.198 | 0.938 | 0.050 |
| hsa-miR-141-5p | 0.966 | 0.000 | 0.849 | 0.050 |
| hsa-miR-223-5p | 8001.591 | 4445.220 | 0.713 | 0.050 |
| Downregulated miRNA | ||||
| hsa-miR-150-5p | 437.928 | 1442.383 | -1.450 | 0.000 |
| hsa-miR-4685-3p | 4.820 | 17.512 | -1.516 | 0.000 |
| hsa-miR-3173-5p | 7.688 | 19.653 | -1.226 | 0.001 |
| hsa-miR-484 | 1324.464 | 2478.547 | -0.838 | 0.001 |
| hsa-miR-204-5p | 18.582 | 53.285 | -1.262 | 0.001 |
| hsa-miR-451a | 882525.102 | 1304912.611 | -0.546 | 0.002 |
| hsa-miR-4745-5p | 0.072 | 2.796 | -1.526 | 0.002 |
| hsa-miR-1306-5p | 4.433 | 14.641 | -1.260 | 0.002 |
| hsa-miR-6815-5p | 5.666 | 15.268 | -1.144 | 0.003 |
| hsa-miR-4732-3p | 78.048 | 182.434 | -1.039 | 0.003 |
| hsa-miR-92a-3p | 27155.615 | 58429.371 | -0.962 | 0.004 |
| hsa-miR-501-3p | 697.870 | 1311.606 | -0.821 | 0.005 |
| hsa-miR-6511b-3p | 1.098 | 5.724 | -1.284 | 0.008 |
| hsa-miR-486-3p | 135096.262 | 240658.136 | -0.755 | 0.009 |
| hsa-miR-483-3p | 11.806 | 32.370 | -1.126 | 0.010 |
| hsa-miR-486-5p | 137121.872 | 241531.605 | -0.742 | 0.010 |
| hsa-miR-6850-5p | 0.990 | 4.660 | -1.199 | 0.014 |
| hsa-miR-6803-3p | 0.450 | 4.295 | -1.181 | 0.017 |
| hsa-miR-6750-5p | 2.714 | 9.667 | -1.143 | 0.017 |
| hsa-miR-1180-3p | 481.900 | 867.740 | -0.751 | 0.019 |
| hsa-miR-550a-3p | 1.732 | 6.826 | -1.146 | 0.021 |
| hsa-miR-550b-2-5p | 1.732 | 6.826 | -1.146 | 0.021 |
| hsa-miR-150-3p | 74.077 | 114.320 | -0.584 | 0.021 |
| hsa-miR-1976 | 4.705 | 12.108 | -1.008 | 0.026 |
| hsa-miR-4732-5p | 174.145 | 318.996 | -0.755 | 0.027 |
| hsa-miR-1229-3p | 0.424 | 3.350 | -1.087 | 0.028 |
| hsa-miR-3605-3p | 9.607 | 24.837 | -0.981 | 0.029 |
| hsa-miR-4753-3p | 0.436 | 2.708 | -1.060 | 0.032 |
| hsa-miR-4742-3p | 6.878 | 17.211 | -0.920 | 0.034 |
| hsa-miR-320a | 52468.459 | 97066.421 | -0.753 | 0.035 |
| hsa-miR-592 | 0.000 | 1.103 | -0.914 | 0.037 |
| hsa-miR-125a-5p | 1558.052 | 3170.278 | -0.819 | 0.039 |
| hsa-miR-146b-3p | 18.873 | 34.714 | -0.758 | 0.040 |
| hsa-miR-320b | 3442.955 | 6415.482 | -0.752 | 0.040 |
| novel_521 | 0.177 | 1.756 | -0.964 | 0.041 |
| hsa-miR-191-5p | 11410.077 | 17378.885 | -0.556 | 0.043 |
| hsa-miR-1228-5p | 10.059 | 20.298 | -0.788 | 0.044 |
| hsa-miR-1285-3p | 87.723 | 144.269 | -0.629 | 0.045 |
| hsa-miR-6833-3p | 0.249 | 1.981 | -0.968 | 0.046 |
| novel_759 | 0.000 | 1.378 | -0.850 | 0.048 |
| hsa-miR-3918 | 0.567 | 2.484 | -0.983 | 0.048 |