Table 3.
Univariate and multivariate analyses of factors affecting CRC patients with peritoneal metastases after palliative primary tumor resection and cytoreductive surgery.
| Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| χ2 value | HR | 95%CI | P value | χ2 value | HR | 95%CI | P value | |
| Age (≦60y vs >60y) | 3.575 | - | - | 0.059 | ||||
| Gender (male vs female) | 0.712 | - | - | 0.399 | ||||
| Tumor location (left vs right) | 4.615 | 0.619 | 0.400-0.959 | 0.032 | 4.019 | 0.618 | 0.385-0.989 | 0.045 |
| Histological type (well vs poor-differentiated) | 3.957 | 1.551 | 1.006-2.390 | 0.047 | ||||
| Tumor size (≦5cm vs >5cm) | 0.801 | - | - | 0.371 | ||||
| CEA level (≦5ng/ml vs >5ng/ml) | 4.661 | 1.614 | 1.045-2.493 | 0.031 | 6.959 | 1.844 | 1.170-2.904 | 0.008 |
| T stage (T3 vs T4) | 1.551 | - | - | 0.213 | ||||
| Lymph node metastasis (N0 vs N+) | 4.487 | 1.995 | 1.053-3.781 | 0.034 | ||||
| PM level (limited vs extended) | 46.668 | 3.684 | 2.534-5.356 | <0.001 | 4.530 | 2.340 | 1.070-5.118 | 0.033 |
| Completeness of CRS (CRS0/1 vs CRS2/3) | 53.634 | 6.982 | 4.151-11.745 | <0.001 | 15.347 | 4.471 | 2.114-9.459 | <0.001 |
| Intraoperative blood transfusion (no vs yes) | 3.571 | - | - | 0.059 | ||||
| NLR value (low vs high) | 12.241 | 2.174 | 1.407-3.359 | <0.001 | ||||
| PLR value (low vs high) | 17.535 | 2.593 | 1.660-4.050 | <0.001 | ||||
| SII value (low vs high) | 14.057 | 2.651 | 1.592-4.413 | <0.001 | 4.048 | 1.772 | 1.015-3.095 | 0.044 |